It has been reported that muscle weakness can be slight or absent in overlap syndromes and anti-HMGCR myopathy, as seen in our cases.[11,12] Muscle weakness might also be absent in anti-SRP myopathy if other organ involvement, like interstitial pneumonia, is the initial manifestation of the disease.[13] In these mild myopathic cases, EMG can support the diagnosis of IIM by directly confirming muscle involvement. This evidence concerns the gene HMGCR and myopathy.