OLAH and rheumatoid arthritis: Additionally, it has been found that the expression of GALNT14 can regulate multidrug resistance in breast cancer cells, function as a prognostic marker for neuroblastoma and non-small cell lung cancer, and predict response to Apo2L/TRAIL-based cancer therapies.[35–38] Studies have shown that OLAH is upregulated in mammary gland epithelial cells and bone marrow-derived mononuclear cells of individuals with rheumatoid arthritis, and it plays a critical role in the synthesis of broad-distribution fatty acids present in breast milk.