COL11A1 and spinal stenosis: Notably, common COL11A1 variants also have been associated with adult lumbar disc herniation and lumbar disc degeneration, as well as DXA-measured bone size, spinal stenosis, and spondylolisthesis (Jiang et al., 2017; Mio et al., 2007; Styrkarsdottir et al., 2019).