Previously, Goldbach-Mansky and associates described a vascular and pulmonary syndrome in patients with gain-of-function variants in the STING-encoding gene STING1 (formerly known as TMEM173) and suggested the name STING-associated vasculopathy with onset in infancy (SAVI) for this autoinflammatory interferonopathy [62]. Here, STING1 is linked to vascular disorder.