Ubiquitin-specific protease 7 (USP7), also known as herpes virus-associated protease (HAUSP), has received widespread attention in recent years due to its close association with the occurrence and development of a variety of cancers, including breast cancer, ovarian cancer, prostate cancer, cervical cancer, and colorectal cancer [9,10,11,12]. Here, USP7 is linked to Familial prostate cancer.