NFKB1 and breast carcinoma: But surprisingly, the previous study showed that LyeTx II from L. erythrognatha venom increased MDA-MB-231 aggressive breast cancer cell proliferation by upregulating activation of p38 and NF-κB pathways and had non-toxicity to three other different breast cancer cell lines (MCF-7, MACL-1 and MGSO-3) [20,21].