AD is a central neurological disease that can lead to progressive cortical functional degeneration, and it is pathologically characterized by the formation of senile plaques in the brain from extracellular β-like amyloid deposits and intracellular tau protein hyperphosphorylation, eventually leading to intracellular fiber tangles in neuronal cells and a loss of neurons [21]. The gene discussed is MAPT; the disease is nervous system disorder.