Among them, MAPK3, AKT1, HSP90AA1, ESR1, RELA, TP53, STAT3, IL2, NFKB1, LCK, JUN, MAPK14, EGFR, ADRBK1, PRKCD, PRKCA, and PRKCZ had higher degree values, indicating that they might be the key targets for the treatment of AD (Figure 1F). This evidence concerns the gene AKT1 and Alzheimer disease.