The ideal cut-off value of baseline E-selectin was 49.3 ng/mL with a sensitivity of 58% and a specificity of 70.3% to predict the outcome of COVID-19 with an AUC value of 0.6523 (95% CI [0.5215–0.7813], p = 0.0286) (Figure 2B). This evidence concerns the gene SELE and COVID-19.