Porcine pentraxin-3 has likewise been shown to have antibacterial effects against S. suis (serotype 2) in vivo in piglets and mice [43].The absence of transcriptional induction of PTX3 during 8067 infection might lead to impaired complement-dependent clearing of the bacterium compared to during S10 and T15 infection. The gene discussed is PTX3; the disease is infection.