Zebrafish receptor (TNFRSF)-interacting serine-threonine kinase 1 (ripk1l) is orthologous to human RIPK1, which participates in Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I) signaling following viral infection [30] and which was upregulated with mVenus-PR8 infection. This evidence concerns the gene RIGI and viral infectious disease.