Interestingly, treatment of the Ewing’s sarcoma cell line RDES with similar concentrations of dCBP-1 also yielded a considerable decrease in p300 protein levels, but no significant difference is tumor cell proliferation and/or viability was observed (Figure S3A,B), suggesting the specific effect of p300 inhibition on CDS tumors growth. The gene discussed is EP300; the disease is neoplasm.