AFP and neoplasm: In addition, the presence of vessel invasion (HR, 1.480; 95% CI, 1.104–1.982; p = 0.009), extrahepatic metastasis (HR, 1.456; 95% CI, 1.092–1.940; p = 0.011), and AFP level > 200 ng/mL (HR, 1.395; 95% CI, 1.036–1.879; p = 0.028) were independent tumor-related risk factors for PFS.