CRP and neoplasm: Male sex [30], older age [10,26,30], trunk tumor location [10], larger tumor size [15,16], extraosseous extension [15], pathological fractures [10,15], metastasis at diagnosis [8,15,16,26,27,28,30], positive surgical margins [10], poor performance status [42], the use of radiotherapy [30], dedifferentiated component histological types of UPS [8,15], a high percentage of dedifferentiated components [8], and high C-reactive protein levels [14] were identified as factors of poor prognosis for survival among patients with DDCS.