TLR4 and glaucoma: Given that RGCs are more vulnerable than glial cells to glaucomatous insult-induced mitochondrial stress [127,128] and that a defect in mitophagy in RGCs is linked to AIBP deficiency [20,118], released mtDAMPs from the Apoa1bp−/− RGCs could be the case that AIBP deficiency clearly linked to mitochondrial dysfunction and TLR4-mediated neuroinflammation via glial cell activation in glaucoma.