We have previously reported that BAFF levels were in excess in the blood of PLHIV relative to their different disease progression statuses; rapid- (individuals whose HIV chronic phase is typically shorter than 2 years before progressing to AIDS), classic- (individuals whose HIV chronic phase typically lasts around 5 years before progressing to AIDS) and viremic slow-progressors (individuals whose HIV chronic phase is typically longer than 10 years before progressing to AIDS) from the Montreal PHI and LTNP cohorts. This evidence concerns the gene TNFSF13B and AIDS.