These pathways are constituted of differentially methylated genes implicated in cancer-related pathways, cell growth, inflammation, and death-related pathways, such as the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT), Mitogen-activated protein kinase (MAPK), the transforming growth factor beta (TGFb), Wnt pathway, and Notch signaling pathway. This evidence concerns the gene WNK2 and cancer.