More specifically, the present study investigated common functional genetic variations in the oxidative stress (PON1, SOD2, and GPX1) and inflammation (IL1B, IL6, IL6R, and miR146a) pathways and their potential association with alcohol addiction and alcohol-related comorbid psychosymptomatology, including obsessive–compulsive, social anxiety, depressive, anxious, and aggressive symptoms. Here, IL6 is linked to Addictive alcohol use.