The prognosis largely depends on local lymph node status with the use of the Ki67 expression assay [166], bromo d-uridine incorporation assay [166], proliferating cell nuclear antigen (PCNA) expression assay [167], AgNoR assay [168], MCT cell ploidy assay, MCT vascularization density assay [169], p53 expression assay [170], KIT gene mutation and expression assay [171], examination of the cell nuclei morphology [172], examination of cellular infiltration depth [173], and examination of tumor localization [174]. Here, PCNA is linked to neoplasm.