MiR-136-5p was found to regulate the expression of the methionine adenosyltransferase 2B (MAT2B) oncogene, whose protein product interacts with Bcl-2-associated anti-apoptotic protein 3 (BAG3), promoting the proliferation, migration, and invasion of RCC cells. The gene discussed is MAT2B; the disease is renal cell carcinoma.