PRKACA and thromboangiitis obliterans: In our study, the downregulated genes associated with TAO were identified as PLP2, CCL4, CCL4L1, CCL4L2, EGR1, RPL9, LAMP2, PRKACA, TOP2B, DGKZ, ANPEP, TCIRG1, NDUFA1, HBB, and RPL32.