Our study aimed to decipher the molecular intricacies associated with PCOS by examining the expression profiles of key genes (11B-HSD1, 11B-HSD2, CYP17A1, CYP11A1, AR) and microRNAs (miR-21, miR-155, miR-34c) in human granulosa cells. The gene discussed is CYP17A1; the disease is polycystic ovary syndrome.