CTCs defined as Hoechst+, CK+, and CD45- cells showed counts of more than eight in 87% of ovarian cancer patients but in none of the healthy volunteers, and the total CTC counts were found to be significantly elevated in the ovarian cancer group (55 vs. 0.5) even though CTC-like cells were identified in low numbers in healthy controls [211]. The gene discussed is PTPRC; the disease is ovarian cancer.