Several proteins, including LY6/PLAUR domain containing 1 (LYPD1), lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1), prothymosin alpha (PTMA), and secretoglobin family 1A member 1 (SCGB1A1) were confirmed to be increased in the urine of ovarian cancer patients compared to benign ovarian tumors, giving an AUC of 0.92 [137]. The gene discussed is LYPD1; the disease is ovarian benign neoplasm.