Autoantibodies against leucine repeat death domain-containing protein (LRDD), stanniocalcin-1 (STC1), and forkhead box a1 (FOXA1) were over-expressed in ovarian cancer patients compared to normal controls and showed an AUC of 0.91, 0.88 and 0.82, respectively. The gene discussed is FOXA1; the disease is ovarian cancer.