In particular, the document identifies four categories of gliomas: (1) diffuse astrocytic and oligodendroglial tumors, which include diffuse astrocytoma IDH-mutant, anaplastic astrocytoma IDH-mutant, oligodendroglioma IDH-mutant, and 1p/19q co-deleted tumors; (2) anaplastic astrocytic and oligodendroglial tumors, including anaplastic astrocytoma IDH-mutant, anaplastic oligodendroglioma IDH-mutant, and 1p/19q co-deleted tumors; (3) GBMs, including GBM IDH-wildtype and GBM IDH-mutant; (4) and other gliomas, such as ependymoma, choroid plexus tumors, and embryonal tumors. The gene discussed is IDH1; the disease is diffuse astrocytoma.