Overall based on our meta-analysis, the CLIA by Diasorin Liaison had the best pooled sensitivity, specificity, and DOR for the detection of measles IgM antibodies with values 0.97 (CI: 0.92–0.99), 0.98 (CI: 0.94–1.00), and 2,559.67 (CI: 737.19–8,887.60), respectively. This evidence concerns the gene CD40LG and measles.