Similar to the results of a study on ApoB and coronary artery disease, Kim et al. found in 14,205 patients without cardiovascular disease, including 2,773 patients with mild coronary artery disease, followed for 5 years, indicating that high plasma ApoB levels were closely related to the prevalence and progression of coronary artery calcium and were not affected by LDL-C levels (33). This evidence concerns the gene APOB and coronary artery disorder.