Our studies confirmed increased monocytes (Ly6c+ CD11b+), monocyte derived macrophages (Ly6c+CD11b+F480+CD64+), and macrophage populations (Ly6c-CD11b+F480+CD64+) in NASH (Figures 1D, G, J). The gene discussed is FCGR1A; the disease is metabolic dysfunction-associated steatohepatitis.