HLA-DPB1 and acute graft versus host disease: They also found that patients with rs9277534A genotype who received HCT from donors with rs9277534A-linked DPB1, a significantly increased risk of acute GVHD was observed in patient with rs927753G-linked DPB1 mismatches compared to patients who received donors carrying rs9277534A-linked DPB1 mismatches (26).