They found that among recipients who received transplants from donors with rs9277534A-linked DPB1 mismatches, the risk of grades II to IV acute Graft-versus-host disease (GVHD) was higher for recipients with rs9277534G-linked DPB1 mismatches than for recipients with rs9277534A-linked DPB1 mismatches (26). This evidence concerns the gene HLA-DPB1 and acute graft versus host disease.