NFKB1 and Cerebral ischemia: After cerebral ischemia, inflammatory transduction mainly depends on NF-κB, mitogen-activated protein kinases (MAPK), phosphatidylinositol 3 kinase/protein kinase B (PI3K/Akt), and phosphoinositide 3-kinase/protein kinase B (PI3K/PKB) signaling pathways.