In the GEO database, mRNA expression of ST3GAL4 was significantly decreased in grade II and III meningiomas (P < 0.05), while the others (ST3GAL1, ST3GAL3, ST3GAL6, ST6GAL1, and ST6GALNAc1) were not (Fig. 7A). The gene discussed is ST3GAL3; the disease is meningioma.