While, SERPINE1 had a detrimental role in LGG, mesothelioma (MESO), STAD, uveal melanoma (UVM), HNSC, LUSC, cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), sarcoma (SARC), PAAD, KIRP, LUAD. This evidence concerns the gene SERPINE1 and sarcoma.