The result indicated that the expression of all SERPINE gene family members were significantly correlated with immune subtype C1 (wound healing), C2 (IFN-γ dominant), C3 (inflammatory), C4 (lymphocyte depleted), C5 (immunologically quiet), and C6 (TGF-β dominant) in pan-cancer (Thorsson et al., 2018; Goldman et al., 2020) (Figure 7C). This evidence concerns the gene TGFB1 and cancer.