However, SERPINE1 was a high-risk factor in LGG, STAD, UVM, MESO, KIRC, HNSC, LUSC, CESC, LUAD, LIHC, SARC, KIRP, GBM, PAAD, and thyroid carcinoma (THCA). Here, SERPINE1 is linked to pancreatic adenocarcinoma.