While, SERPINE1 had a detrimental role in LGG, mesothelioma (MESO), STAD, uveal melanoma (UVM), HNSC, LUSC, cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), sarcoma (SARC), PAAD, KIRP, LUAD. Here, SERPINE1 is linked to pancreatic adenocarcinoma.