TMEM16F also plays important roles in membrane fusion (Zhang et al., 2020; Whitlock and Chernomordik, 2021), membrane repair (Wu et al., 2020), viral infection (Zaitseva et al., 2017; Sim et al., 2022), and phagocytosis by macrophages (Ousingsawat et al., 2015) and microglial cells (Batti et al., 2016; Zhao and Gao, 2019). The gene discussed is ANO6; the disease is viral infectious disease.