Radiation therapy (RT) has been linked to inducing ferroptosis in tumours through diverse pathways (Lei et al., 2020), such as ROS production, GSH depletion, ACSL4 upregulation, and SLC7A11 inhibition (Azzam et al., 2012; Lei et al., 2020) (Figure 1). Here, SLC7A11 is linked to neoplasm.