The GSEA enrichment analysis revealed that the DERATGs in the GSE55235 dataset exist and are also significantly enriched in the upregulated pathways, such as an intestinal immune network for immunoglobulin (Ig)A production, allograft rejection, autoimmune thyroid disease, etc. (Fig. 6A), and are also significantly enriched in the downregulated pathways, such as ribosome biogenesis in eukaryotes, basal cell carcinoma, mitophagy-animal, and so on (Fig. 6B). This evidence concerns the gene CD79A and autoimmune thyroid disease.