For example, RPL10 R98S, a somatic arginine-to-serine missense mutation of ribosomal proteinL10 (RPL10) at residue 98 (R98S) that is present in nearly all patients with T-ALL carrying mutant RPL10, promotes the progression of T-ALL by activating survival signaling pathways [119–121]. Here, RPL10 is linked to acute lymphoblastic leukemia.