After undergoing epithelial-mesenchymal transition, cancer cells use TGF-β to trigger the production of pro-tumorigenic cytokines such as platelet-derived growth factor (PDGF), hepatocyte growth factor (HGF), ILEI (interleukin-like EMT-inducer), and epidermal growth factor) [48]. The gene discussed is TGFB1; the disease is cancer.