Therefore, to investigate the potential association between those cytokines and the presence of CD4+ , Foxp3+ , GZMB+ , CD4-Foxp3+ and CD4-GZMB+ markers, positive cells counts in the tonsils of patients with distinct EBV infection statuses and viral latency profiles were correlated with IL10+ and TGF-β+ expression, evaluated by IHC. The gene discussed is GZMB; the disease is Epstein-Barr virus infection.