Therefore, there may be an advantage in local prostate cancer staging for PSMA PET tracers that exhibit lower urinary excretion such as [18F]PSMA-1007, compared to the primarily urinary excreted tracers [18F]DCFPyL, [18F]-JK-PSMA-7 and [68Ga]Ga-PSMA-11. The gene discussed is FOLH1; the disease is Familial prostate cancer.