To assess the extent to which increased T-cells in ATRX-deficient tumor-bearing mice promoted overall survival, we depleted CD4+ and CD8 + T-cells in C57BL/6 immunocompetent hosts bearing CT2A AtrxWT or Atrx KO-B tumors (Fig. 4d, e; Supplementary Fig. 9). The gene discussed is CD8A; the disease is neoplasm.