FASN and metabolic dysfunction-associated steatotic liver disease: For example, some natural plant medicines, such as Schisandrin B, Arteether, and Limonin, can effectively inhibit the activation or infiltration of M1 macrophages, as well as the secretion of proinflammatory factors, by inhibiting FASN-mediated new fat formation and the lipolysis process, thereby exerting a protective effect on NAFLD [105–109].