NDUFS4 and Leber hereditary optic neuropathy: We used 5 different antibodies against histone acetylation and methylation, H3K18Ac, H3K27Ac, and H3K4Me3 for activation marks and H3K9Me2 and H3K27Me3 for repressive marks, in this study to determine differences in histone enrichment in NDUFS4 in LHON.