FAP and metastatic malignant neoplasm in the lymph nodes: In addition, more favorable uptake of 68Ga-FAPI than 18F-FDG in terms of TLR was presented by both lymph node metastases (18.65 ± 10.50 and 5.64 ± 2.81, P < 0.001) and bone metastases (21.99 ± 9.70 and 4.94 ± 2.90, P < 0.001), which indicates that FAP-targeted radioligand therapy may exert a strong antitumor effect with little damage to organs at risk (32).