The experimental data showed that apoptosis-related protein (Bax) expression was confirmed to be significantly increased and Bcl-2 expression and Bax / Bcl-2 ratio was significantly decreased in the MI group compared with S group, which was significantly improved by 5 weeks of aerobic platform running exercise, as shown in Fig 4A–4C. Here, FAM215A is linked to myocardial infarction.