Genetic testing, including comparative genomic hybridization microarray to rule out copy number variation, mitochondrial DNA sequencing, and next-generation sequencing of a panel of 29 congenital and acquired lipodystrophy genes (ADRA2A, AGPAT2, AKT2, ATP6V0A2, BANF1, BSCL2, CAV1, CAVIN1, CIDEC, FBN1, IGF1R, KCNJ6, LIPE, LMNA, LMNB2, MFN2, PCYT1A, PIK3R1, PLIN1, POLD1, PPARG, PSMA3, PSMB4, PSMB8, PSMB9, SPRTN, TBC1D4, WRN, ZMPSTE24), including mitofusin-2 (MFN2) associated with multiple lipomatosis, was unrevealing for additional diagnoses beyond MMUT MMA. The gene discussed is CAVIN1; the disease is acquired lipodystrophy.