Finally, by performing qRT-PCR, we validated that the expression of GYS1 and SLC7A11 were upregulated, whereas those of NCKAP1, NDUFS1, NUBPL, OXSM, RPN1, and SLC3A2 were downregulated in ccRCC compared with those in the para-carcinoma tissues. This evidence concerns the gene SLC7A11 and nonpapillary renal cell carcinoma.