Among them, GYS1 and SLC7A11 were highly upregulated in ccRCC tissues, whereas LRPPRC, NCKAP1, NDUFA11, NDUFS1, NUBPL, OXSM, RPN1, and SLC3A2 were downregulated in ccRCC tissues. The gene discussed is NUBPL; the disease is nonpapillary renal cell carcinoma.