POLQ and neoplasm: POLQ exhibits elevated expression levels in diverse malignant tumor tissues, such as lung adenocarcinoma, gastric cancer, colorectal cancer, breast cancer, cervical cancer, and oral cancer, and its presence has been linked to unfavorable prognostic outcomes in a number of tumors (Allera-Moreau et al. 2012; Ceccaldi et al. 2015; Lemee et al. 2010; Pillaire et al. 2010).