YTHDF1 and cancer: In numerous cancers, there is a consistent observation of dysregulated expression of key enzymes involved in m6A modification, including "writers" (such as METTL3, METTL14, WTAP), "erasers" (like FTO, ALKBH5), and "readers" (including YTHDF1, YTHDF2, YTHDF3) (Sun et al. 2019).