Meanwhile, we checked the mRNA and protein level of Sod2, the lower Sod2 mRNA level within PT was found in CIN or UUO sample comparing with that in con kidney (Fig. 4D) and lower Sod2 protein level was also found in UUO kidney compared with con kidney (Fig. 4E). The gene discussed is SOD2; the disease is cervical squamous intraepithelial neoplasia.