We also measured the abundance of neutrophils in urine sediments (pyuria) following infection with UTI89 and found that they were significantly increased in Slpi−/− mice compared to Slpi+/+ mice 7 hours after infection (P = 0.006) but returned to Slpi+/+ levels by 24 hpi (Fig. 3B). The gene discussed is SLPI; the disease is infection.