Su et al. found that LncRNA HAND2‐AS1 sponged miR‐143‐3p/TNFAIP3 induced apoptosis and inhibited proliferation, invasion, migration, and inflammation of RA‐FLSs8; Sun et al. found that Lnc‐AL928768.3 promotes proliferation, invasion, and inflammation while inhibits apoptosis of RA‐FLS via activating lymphotoxin β‐mediated nuclear factor kappa B (NF‐κB) signaling.9 This evidence concerns the gene HAND2 and rheumatoid arthritis.