In this study, we found that among CHB patients with normal ALT levels, the proportion of liver fibrosis was 33.3% (19/57 cases) (using FIB‐4 > 1.45 as an indicator of liver fibrosis) or 8.7% (5/57 cases) (LSM > 7.4 as an indicator of progressive liver fibrosis). This evidence concerns the gene GPT and Hepatic fibrosis.