NFKB1 and periodontitis: In addition, certain bacterial components induce the change of miRNA expression, and dysregulated miRNAs regulate the production of inflammatory factors in the periodontal pocket, mediate the expression of intercellular cell adhesion molecule‐1 and E‐Selectin, negatively modulate the TLR signaling pathway and NF‐κB pathway, and promote neo‐angiogenesis in periodontitis.14